LINA02H3 Lecture Notes - Lecture 7: David Baltimore, Rna Virus, Dna Polymerase
Document Summary
All rna viruses (except retroviruses) must synthesis an rna pol ii only reads. If you"re and rna virus, you have to make your own rna- Viruses in these two groups differ in how their replication cycle begins: positive strand rna viruses (plus strand viruses) Sense strand- the strand that can be directly translated into viral proteins: negative strand (minus strand viruses) Antisense strand- can not be directly translated into proteins. Complementary to the sense strand: dna genomes. Use the dna-dependent rna polymerase from the host cell to convert dna rna. Dna polymerase reads a strand of dna and helps produce a complementary strand. Converts from a single strand double strand. The host cell becomes a factory for the expression and replication of viral genomes. The molecular pathway that lead to the synthesis of early viral proteins from viral messenger rnas depend on the genome"s: chemical nature, strandedness (double or single) David baltimore used those two factors to create the classification.
