NROC64H3 Lecture Notes - Lecture 10: Inferior Cerebellar Peduncle, Middle Cerebellar Peduncle, Cerebellar Peduncle

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4 Jan 2018
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Cerebellum receives inputs from the cortex via: corticopontocerebellar pathway, corticorubroolivocerebellar pathway. Cerebellum outputs to the motor cortex via: disynaptic dentatothalamocortical pathway. Fibers from dentate nucleus (10) connect to the ventrolateral motor thalamus (1), which projects to areas 4 and 6 in primary cortex (3) 2 pathways start from the motor cortex, and all pathways end in cerebellum. Deficits: appendicular ataxia: disturbances in carrying out voluntary, planned movements by the extremities. Anatomy of the basal ganglia: caudate nucleus: part 1 striatum, putamen: part 2 striatum, globus pallidus, subthalamic nucleus, substantia nigra: reciprocally connected to basal ganglia. Cortex striatum (main input of bg) globus. Cortex: projects back to basal ganglia, for(cid:373)s a (cid:373)otor (cid:862)loop(cid:863, function of the motor loop: selection and initiation of willed (voluntary) movements. At rest: globus pallidus are active and inhibitory to thalamus (like the omnipause neurons in eye movements) Excitation from cortex excitation putamen inhibits globus pallidus.

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