NROB60H3 Lecture Notes - Lecture 10: Climbing Fiber, Purkinje Cell, Inferior Olivary Nucleus
Document Summary
Involved in procedural memory: allows for coordinated movements of muscles and joints by synthesizing data from brain stem, spinal cord, cerebral cortex, and sensory info from muscles. Ltd: a long-lasting weakening in signal transmission between neurons, best characterized in the hippocampus and cerebellum. Motor planning for extremities: intermediate hemispheres. Distal limb coordination: vermis and floculonodular lobe. Three highways in/out of cerebellum: inferior peduncles. Connect the medulla to the cerebellum: middle peduncles. Connect pons to the cerebellum: superior peduncles. Cerebellum: lots of folia (gives cauliflower-like appearance, allows fine motor functions, intricacies of voluntary movement. Enter granule cell layer and synapse on dendrites. Granule cell axons travel to molecular layer and end in t. Parallel fibres and target purkinje cells run parallel to surface : climbing fibres. = axons from nucleus in medulla called the inferior olive. Go straight to purkinje cell layer and up dendrites; each climbing fibre targets one.
