NROC64H3 Lecture Notes - Lecture 2: Agnosia, Two-Streams Hypothesis, Parietal Lobe

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13 Sep 2017
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They will synapse with either rod or cones. Axons then transmit it directly/indirectly to the ganglion cells. Diffuse (cid:272)ells: takes i(cid:374)fo fro(cid:373) (cid:373)a(cid:374)(cid:455) differe(cid:374)t photore(cid:272)eptors. Not required for high acuity but important for sensitivity. On cells increase signal with increase in light. On bipolar cells has mglur6 which is an inhibitory receptor. Off becomes depolarized by the glutamate causing the nt to be released to the ganglion cell. In light, cone becomes so no glutamate is released. On bipolar cell depolarizes which causes neurotransmitter release, and hyperpolarizes off receptors so not nt. Flat bipolar cells: dendritic tips are on surface of photoreceptor (mainly off variety) Invaginating bipolar cells: goes into photoreceptors (mainly on variety) This causes depolarization of the horizontal cells which then release. They can synapse onto the ganglion but through the amacrine cell. These mainly inhibit the cone pathway so the rod pathway can take place.

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