PSYB20H3 Lecture Notes - Lecture 3: Congenital Heart Defect, Organogenesis, Neurodevelopmental Disorder

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21 Aug 2018
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Principles of growth: cephalocaudal principle = dictates that development proceeds from the head to the lower part of the trunk. This is why babies have big heads because it grows first: proximodistal principle = development proceeds from parts near the centre of the body to outer ones. The first thing to develop is the nervous system then the heart and last is finger nails, tips etc: cell migration: movement of newly formed cells away from their point of origin. Stem cells: embryonic stem cells = have no fixed fate or function (unspecialized). Can be induced to become tissue- or organ-specific cells with special functions. They are not specific cells, they could become any cells. They could be induced to become a certain cell: cell differentiation = cell starts to specialize in specific structure and function, a cell will trigger to become a special cell eg. ) heart approx.

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