PSYB65H3 Lecture Notes - Lecture 4: Deep Brain Stimulation, Wilder Penfield, Neuroanatomy
Document Summary
In patients with severe depression, brain region area 25 is overactive. Deep brain stimulation can help suppress its activation with continuous stimulation. Channel; folded proteins to allow certain things through (tunnel) Gate; channel with a lift door that opens at certain times. Pump; atp used to push things across membrane against [ ] gradient. Movement of water can tell us about the integrity of white matter. Studying neuroanatomy using staining and histological ways post-mortem. Animal models are used a lot due to high degree of control and manipulation to them and being able to observe their actions throughout their short lifespan. Can modify the brain and see how behaviour is affected; can create hypothesis and test them. Brain lesions; can measure behaviour before and after; ablation - removal or destruction of tissue, either by burning or chemically. Stereotaxic apparatus; placing probe inside brain to affect very specific regions of the brain.
