PSYB64H3 Lecture Notes - Lecture 4: Nitric Oxide, Saltatory Conduction, Neuromodulation
6 Feb 2017
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There will be a written part on the test! Ap if you make it more negative: typically, you are making the cell more negative if you hyperpolarize it. Can an ap occur? have to reach threshold for it to occur, and it happens all-or-nothing: when you depolarize a cell, you are making it more positive. Now a little about psychopharmacology (starting on slide 9 lecture 4): you are only responsible for content covered in slides for chapter 4 (psychopharmacology)! Examples of commonly used drugs and their effects! Drug actions at the synapse: agonists enhance the activity of a neurotransmitter, antagonists reduce the activity of a neurotransmitter, so, these act in opposite ways! Think back: how could a drug affect postsynaptic activities, it could affect binding at the receptor sites (interfere or enhance binding), it could affect reuptake, it could affect activation, we can interfere at any stage with the drug!
