PSYC62H3 Lecture Notes - Lecture 1: Anhedonia, Monoamine Neurotransmitter, Nicotine
5 Jan 2015
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Anhedonia: lack of interest or pleas. in actt want to be alive not nec. planning out suicide. Reactivat. of unpleas. mem"s, nuc. accumbens - not as activated as someone non-depressive. Dep. can be manifest through diff. nt syst"s not just monoamine nt"s b/ this hyp. is used to create drugs. Mao inhibitors prevent mao from breaking down mao transmitters. Irreversible inhibitors: inhib. and attach and that"s it; have to be cleaned up later. Reversible: temp. will bind to mao and allow other compounds to displace the monamines from the mao different impacts the different agents have depending on molecular form. Limited clinical use of first class mao inhib"s (cheese reaction) Dep. syst"s improve b/ increased hb, high bp/hypertension b/c of relation to symp.
