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Lecture 20

Lecture 20.docx

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Steve Joordens

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PSYA02 Biological Treatments - Assumes that some (all?) disorders are ultimately caused by abnormal neural or other physiological functions - Drug therapy - Psychotherapy - This is not really the beginning or the end - The “main” approach to treatment Norepinephrine, Dopamine, Serotonin - The three main types of neurotransmitters - What dangers can be found of this? - Any one of these neurotransmitters has effects on multiple parts of the brain - One big thing to avoid is side effects - Norepinephrine is related to the cortical regions as well as the cerebellum; relates to alertness and energy; adjusting one areas = adjusting all areas related to the neurotransmitter’s region (the planet x rule) - Dopamine also has the same idea and so does serotonin - Serotonin affects most of the blood - Take home message: the drug will give the desired effects as well as its side effects; they often get in the way of therapeutic techniques - The brain is not like a car engine; the brain learns the context (through classical conditioning) that the natural drug can be stopped due to an external source coming in, therefore stops producing its own, thus the strong addiction/craving for the drug (how drug addiction works) Drug Therapies In the case of Schizophrenia, drug therapies are the “way” to go Antipsychotic Drugs: - Chlorpromazine (Largactil/Thorazine) dramatically reduces the positive symptoms of Schizophrenia - Apparently works by blocking dopamine receptors - Long term use leads to tardive dyskinesia (lip smacking, drooling) Antidepressant/Antimanic: - Sometimes for reasons unknown, the drug is meant is made to feel good, 95% of people who take it feel better, but 5% feel worse - Shows that sometimes the drug may not work, and that there is more to drugs that we do not understand yet - Trycyclics: Slow the re-uptake of norepinephrine and serotonin; many side effects (weight gain, poor concentration) (Depression) - Monoamine Oxidase Inhibitors (MOI): Prevent enzymes from destroying norepinephrine and serotonin; also many side effects (high BP, blurred visio
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