PSYC31H3 Lecture Notes - Lecture 2: Frontotemporal Dementia, Neurofibrillary Tangle, Extrapyramidal Symptoms
Document Summary
Dementia of the alzheimer"s type (dat) most common type. Starting point: medial temporal lobes: the hippocampus is affected very early on one of the earliest symptoms is memory loss. End point: all across the cortical (frontal lobes: leads to atrophy of the brain. Neurofibrillary tangles (breakdown of neurofibrillary components within the cell, usually responsible for taking information from the soma to the synapse) and beta-amyloid plaques (these are outside of the cell) Cannot diagnose this entirely before a person is dead many dementias seem similar so you actually need to see post-mortem to make sure it"s actually alzheimer"s. Meta-analytic review of structural and functional imaging studies. Goes from hippocampus temporal lobes to occipital to parietal and then to frontal lobes: memory is affected then language then vision problems then apraxia then executive functions. Slow onset/progression: starts in frontal lobe (sometimes in temporal too) Changes in social behaviour, personality, speech as the frontal lobe is affected.
