BIO120H1 Lecture Notes - Lecture 15: Histidine, Only Time, X-Ray Crystallography
shdhhfhshhpla3806 and 40102 others unlocked
36
BIO120H1 Full Course Notes
Verified Note
36 documents
Document Summary
Lecture outline: overview of dna replication, dna replication in bacteria. Only time you need dna replication is when cell divides. Every single cell in organism"s body contains entire genome required to build entire organism. Watson & crick worked out structure of dna used x-ray crystallography & models. 2 hypotheses: dna synthesis is conservative, dna synthesis is semiconservative. Conservative 1 daughter cell (when cell divides) gets all of original parental strand & other gets completely new synthesized strand. Semiconservative use both strands as template, 1 of original strand goes into 1 cell & other goes into other cell. Both daughter cells get 1 of original strand & 1 new synthesized strand. Important implications for error rates if you have 1 original copy & 1 newly synthesized copy, important implications for how error checking may happen, how mistakes might be corrected, etc. 3 possible models: unidirectional growth of single strands from 2 starting points.