BIO120H1 Lecture Notes - Lecture 4: Probability Distribution, Mendelian Inheritance, Base Pair

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19 Sep 2018
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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Heredity: progeny resemble their parents more than unrelated individuals. Selection: some forms are more successful at surviving & breeding than others in a given environment. Occurs at a low but variable rate. Any given base is unlikely to be mutated from one generation to the next. May differ b/c of location or environment. Neutral can still spread & evolve by chance (genetic drift), most are lost b/c don"t do anything. Beneficial mutation is a mistake that works. Variation is there to begin with but environment is selective pressure. Environment has effect on rate of mutation. Genome sequencing technology allows us to find rate of mutation. Every base pair in entire human pop genome is being mutated on avg 92 times every generation. Recombination + independent assortment = unique genetics after meiosis. Theory of blending inheritance postulated genes from both parents mix irreversibly. Creates problem for evolution by natural selection. Started with hybrid cross of pure-breeding lines.