BIO120H1 Lecture Notes - Lecture 4: Dna Replication, Mutation Rate, Mutation
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BIO120H1 Full Course Notes
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Document Summary
Progeny resemble their parents more than unrelated individuals. Some forms are more successful at surviving and breeding than others in a given environment. Where does heritable variation come from: mutation. Mutation is an unstoppable phenomenon: despite cellular mechanisms to correct errors during dna replication. Mutation is not directed by the organism or the environment: random with respect to effect on tness. Rate depends on the type of mutation: can also vary among genes. Environment can affect mutation rate: mutagens, high temperature, high. Uv environment might increase the rate of mutations. Insertions/deletions: changes in repeat number, chromosomal rearrangements. Dna ngerprinting may be affected (dna does not match criminal) The rate is extremely low, the correcting enzymes are often really good. Entire human population: every base pa ir is being mutated on average of about. Causes legs to grow out of the y"s head. This is done in the lab , it shows the range of affect a mutation can have.
