BIO120H1 Lecture Notes - Lecture 5: Genetic Drift, Population Genetics, Natural Selection
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BIO120H1 Full Course Notes
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R. a fisher, j. b. s haldane, s. wright: mutation. 1. increases genetic diversity: ultimate source for genetic variation, caused by errors during replication (not directed, recombination. Introduces new combinations of mutations into a population: random genetic drift. 1. (decreases genetic diversity: random sampling effects every generation, becomes more important as populations become smaller, you can get evolution with natural selection, by chance, natural selection. 1. increases genetic diversity: migration in uences the structuring of diversity over a large spatial scale. Average frequency of heterozygous individuals per gene loci. Less t types maintained by repeated mutation: diverse selective forces favouring diversity, heterozygote advantage, frequency-dependent selection, tness varies in space and time. I. e. rare-types are always favoured: variation selectively neutral, different types do not differ in their tness hence not eliminated by selection. Low polymorphism: wild type is normal genotype. How natural selection is actively varying population genetics. There should be plenty genetic variations in that case.