BIO120H1 Lecture 5: Lecture 5 - The maintenance and measurement of genetic variation
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BIO120H1 Full Course Notes
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Lecture 5 - the maintenance and measurement of genetic variation. People fisher, haldane, wright, morgan, muller,ford, dobzhansky, lewontin. 1930-50 theoretical population genetics was initiated by fisher, haldane and. Wright and provided the foundations for neo-darwinism and the new. They showed that continuous variation and darwinian natural selection were entirely consistent with mendel"s laws. They also demonstrated the evolutionary significance of genetic variation leading to several key questions and development of the field of ecological & evolutionary genetics. Important parameters used to measure patterns of genetic variation. Proportion of gene loci that are polymorphic. Note: distinguish genetic polymorphism(2 alleles) and phenotypic polymorphism. E. g. gene1 bw gene2 b gene3 bw = polymorphic. Average frequency of heterozygous individuals per gene locus* *a site on a chromosome that is usually a gene. What processes influence patterns of genetic diversity: mutation + Caused by random errors during replication: random genetic drift- Definition: genetic drift refers to random fluctuations in allele frequencies due to chance events.
