BIO130H1 Lecture Notes - Lecture 7: Lipid Bilayer, Membrane Protein, Drug Delivery
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BIO130H1 Full Course Notes
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Document Summary
Saccharomyces cerevisiae: budding yeast, singled celled eukaryote, cell wall, tough protective outer coat. Lysosomes: degradation of cell parts that are no longer needed. Extracellular matrix: specialized material outside of cell. Cell wall: tough protective outer coat, can be found in bacteria, prokaryotes and unicellular eukaryotes as well. Vacuole: one functions similar to a lysosome, one is used for storage. Cytoplasm: contents of the cell outside of the nucleus. Cytosol: aqueous part of the cytosol, not including membrane bound organelles, includes ribosomes, protein structure and cytoskeleton. Functions that occur at membranes: compartmentalization, scaffold for biochemical activities, selectively permeable barrier, transporting solutes, responding to external signals, interaction between cells. Fluid mosaic models: phospholipids move, many different phospholipids and proteins. Amphipathic: different biochemical and biophysical properties on different surfaces (phospholipids) Membrane lipids: have a polar head that interacts with water, the hydrophobic tails that interact with other hydrophobic tails, they will spontaneously self-associate into a bilayer.
