BIO130H1 Lecture Notes - Lecture 20: Kinesin, Globular Protein, Actin

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6 Apr 2016
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BIO130H1 Full Course Notes
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BIO130H1 Full Course Notes
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Another commercial shown for biologists, this time for pcr. Harvard"s animated video of the cell - same video from beginning of the course (inner life of a cell) These neurons are long and go from spinal cord to finger tips. Problem: how does a neurotransmitter synthesized in er get to synapse. Note how er and golgi are in the cell body. Two proteins that make it up are dynein and kinesin. Dynein movement: towards the cell body (of neuron) Kinesin movement: towards the axon terminus (of neuron) Below is the neuron and shown, by chance, the plus is at the synapse. Other cells may not be in this kind of conformation. Epithelial cell for example, does not have an axon terminus but do have a plus end. Both dynein and kinesin can be attached to a vesicle. Other proteins will dictate which one will work. There are other kinesin that move oppositely but that isn"t req for this course.