BIO130H1 Lecture Notes - Lecture 3: Dna Profiling, Interphase, Mitosis

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19 Apr 2016
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BIO130H1 Full Course Notes
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BIO130H1 Full Course Notes
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Week 3: genomes and chromosomes: genomes, bacterial dna packaging. Karp: 411 414, 400 406 (skip human perspectives) Nature and science journals demonstrate genome sequences of model organisms. Hundreds of eukaryotic genomes and thousands of prokaryotic genomes have been sequenced. Approximately 90% of the human genome has been sequenced. Sequencing has become a lot cheaper, quicker, and easier to do. The chemical sequencing of the genome isn"t necessarily the hardest part of genome sequencing. Approximately 65% of neanderthal genome obtained from ancient dna samples from fossils. Approximately 1-4% of dna from anatomically modern europeans and asians may have originated from. Much of this neanderthal-derived dna related to immune function, bone formation/shape, skin o. E. g. , base response to bacterial pathogens or seasonal allergies. 3 billion base pairs per genome (haploid after meiosis) One maternal + one paternal genome = you. Xx female, xy male: only 1 x chromosome of each is transcriptionally active. Source of antibiotic resistant genes (1 1000kb)