BCH210H1 Lecture Notes - Lecture 2: Post-Translational Modification, Histidine, Methylene Group

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Stavroula Andreopoulos

Document Summary

Lecture 2 outline: ph 7. 2 is about standard for the inside of cells. 20 amino acids: names, structures, and properties ph and acid basics. These are all in the zwitterionic form: all have the alpha carbon, with hydrogen off the carbon, glycine is the smallest amino acid with only hydrogen, often glycine and alanine at contact points of tightly packed amino acids. Small side chain (methyl group) occupies little space: hydrophobic side chain, but not overly so. Few methyl groups and ch group, so it"s much more hydrophobic than alanine. Tends to be find buried inside protein structures, away from water: hydrophobic, resembles valine with an extra methylene group, so categorized as a little more hydrophobic. Interesting amino acid most common amino acid in soluble proteins, most common amino acid in membrane proteins: has a hydrophobic structure (alkyl chains), buried within the structure of protein.