BCH210H1 Lecture Notes - Lecture 19: Trypsinogen, Deamination, Mental Chronometry

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Stavroula Andreopoulos

Document Summary

Thursday, october 19th, 2017 10am-11am: be able to recognize the six classes of enzymes, based on key. Specificity for enzymes and the active site (characteristic key residues that carry out the catalysis) If the enzyme doesn"t have a substrate, it won"t carry out a particular reaction (i. e. , don"t make a substrate available) It"s a reversible modification (can remove the phosphate) Pyruvate dehydrogenase is an oxidoreductase takes pyruvate + Pd kinase is a transferase which uses atp to phosphorylate pd (red) making it inactive if high acetyl coa. Pd phosphatase (hydrolases) cleaves off phosphate, activating the enzyme again (green) if low acetyl coa. Phosphorylase kinase activates pb by phosphorylating it to make. Pa, which is responsible for breaking down glycogen (polyglucose) Pa takes pi and cleaves off one glucose residue while simultaneously attaching phosphate, so you generateg1p + glucose polymer (glucn-1: not a phosphorylation reaction because it"s using pi for cleavage of glucose and phosphorylation = phosphorylysis reaction.