BCH210H1 Lecture : Tutorial notes
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BCH210H1 Full Course Notes
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Soon yi part v: if glycogen has a caloric value of 4kcal/g and fat has a caloric value of 9 kcal/g. polyunsaturated when they are substrates for cox, get eicosanoids not involved in inflammation. Adrenaline, glucagon effects on liver and muscle cells. Increase fatty acid activation: decreases glycolysis only in liver. Inactivates pk and pfk2 y both enzymes that increase glycolysis. On adipose tissue: free fatty acids released, fat originally stored in triacylglyceride form three fatty acids attached to glycerol. Activate fatty acid: hs-coa coenzyme, binds to thio bond high energy bond, 2 atp molecules needed to activate, activation occurs in cytoplasm. Then translocation: allows for regulation of fatty acid metabolism, transfers fatty acid chain to carnitine molecule. Dehydrogenation removing two hydrogens (oxidation) generate nadh or fadh. Hydration adding water to beta carbon. Dehydration generate another nadh, to be used for energy. Where enzyme activity occurring always on beta carbon: second carbon in chain.