BIO130H1 Lecture Notes - Lecture 4: Cell Cycle, Chromatin, Heterochromatin

• School: UTSG
• Department: Biology
• Course: BIO130H1
• Professor: Jane Mitchell

Document Summary

*modern humans with non-african ancestral genomes contain approximately 1 - 4 % +genomes can come in all sizes (bp: base pairs) *mitochondria protein are transcribed in nucleus, translated in cytoplasm, translocated to surface of mitochondria, and assemblaged in mitochondria. Amoeba has larger genome than human an organism"s complexity and size are not reflected in genome size. Protein or rna does not reflect the number of genes. In prokaryotes, the dna is condensed through folding and twisting about 1000 fold. Bound together, dna + protein form the nucleoid. Important components of this packaging are: positively charged polyamines (stretches of amine containing compounds shield the charges on the (-) charged dna strands. Total length of dna in human body: 2 x 1010 km. *karyotype (shapes and numbers of chromosomes determine the genetic disease) Array artificial of paired chromosomes in numerical order. Denature the probe with fluorescent (for specific, and also denature the target dna.