CSB202H1 Lecture Notes - Prostate, Epitope, Sipuleucel-T
3 Jun 2013
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Vaccines targeted for infection for protection against infection prophylactic so given before the infection. Prophylactic vaccine aim to prevent infection or disease . In this individual, immune system not controlling infection. Immune system capable of using different means to attack cells so it doesn"t seem to agree with supposition that immune system could not control tumour in cancer patient. In contrast to pathogen, tumour looks like self so to immunize against it, by nature it is an. Autoimmune response successful vaccine activates, reactivates immune system to allow to detect transformed cells . Problem pathogen nmeng capsule looks like sugar that expressed during neonatal development case of where antigen resembling self so no immune response. In most cases, unless cancer driven by pathogenic infection, have to develop immune response. Spuleucel provenge immune based drug against. Not a single formulation personalized medicine example.
