CSB327H1 Lecture Notes - Lecture 15: Type I Collagen, Type Ii Collagen, Vascular Smooth Muscle

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Csb327 lecture 15 notes (november 21, 2012) sibling family and tissue mineralization. 2 the sibling family of calcium binding glycoproteins. Opn appears to have the opposite biological effect. While bsp is found primarily in mineralized tissues, opn has a much broader distribution. It may contribute to preventing our soft tissues from undergoing abnormal mineralization. Do we have a modified nucleator, or are tissues prone to mineralize and it is more important to prevent their mineralization: we know ectopic mineralization occurs. One example is smooth muscle cell in the cardiovascular system can promote mineralization, which is not good because you eventually form a plaque. Video: http://www. youtube. com/watch?v=0dv1bwe2v6c, estrogen promotes an increase in bone mass. When you go through menopause, it is very controversial if you should be taking estrogen therapy because it can also promote metastatic behaviour of cells. 4 small integrin-binding ligand, n-linked glycoproteins (sibling) and tissue mineralization.

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