CSB332H1 Lecture : Lecture 21

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Dark (rest): inward current into outer segment depolarization. Vertebrate photorecs respond w a hyperpolarization graded according to intensity of flash. R info falls on left side of retina. Optic nerve fibers arise from ganglion cells in retina, end in lgn (lateral geniculate nucleus part of thal) Lgn axons project to the cerebral cortex. Output from each retina divides at optic chiasm to supply lgn on each side. R side of each retina projects to r lgn: r visual cortex receives info exclusively from l half of visual field. Ex. ppl w damaged r cortex = blind in left visual field. Neurons converge & diverge extensively at every stage: ex. human eye contains 100mil rods & cones but only 1mil ganglion cell axons. Each ganglion cell axon supplies many geniculate cells. 3 principal features of photoreceptor structure: outer segment: light absorbed by visual pigment, packed with recs, change membrane pot. Inner segment: nucleus, ion pumps, transporters, ribosomes, mitochondria, er.

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