CSB429H1 Lecture Notes - Lecture 3: Maternal Effect, Oogenesis, Blastoderm

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Contains polar granules = large complex cels of protein and rnas. Molecules to start making granules/ the starting protein is oskar (in flies not conserved out of insects) Maternal factors: all factors put into the egg during oogenesis. Maternal mrnas specifically localized to germ plam. 3" utr of these mrnas imp for the localization. 30% of the rna in germ cells comes from the germ plasm. Blastoderm: large portion of the maternal mrna are degraded w/ the exception of the. Degradation of rnas in somatic but not the pgcs. Early embryo: - no transcription b/c it has things from oogenesis ] the mitosis cycle only consists of m and s phase (g1 and g2 are eliminated required for transcription) They preserve the character of the original cell/zygote. Zygotic transcription starts in the somatic cells; they determine their own fate. Very potent tfs are made that determine fate.

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