CHM247H1 Lecture : Aromaticity.pdf
Document Summary
Aromatic historical term refers to fragrant substances, usually isolated from natural products: examples: Vanillin aroma/flavour of vanilla, derived from vanilla beans; a very common aromatic compound. Quinine powerful antipyretic, bitter flavour of tonic water ; isolated from the bark of the cinchona tree (native to the andes mountains); for centuries it was the only effective treatment for malaria because of its powerful antipyretic properties. Today, aromatic refers to benzene and its structural derivatives (have similar structure and reactivity: many widely-used drugs contain a benzene ring. A psycho-therapeutic used to treat depression and panic disorders. A source of benzene; different fractions of the petroleum distillation can be used for different things. Many aromatics retain traditional or trivial" names; iupac allows these names. Use benzene" as the suffix, when the substituent is of low priority. Use benzene" or benzo" as a prefix with a substituent of high priority (ie/highly oxidized or highly reactive often being highly oxidized results in greater reactivity)
