CSB351Y1 Lecture Notes - Lecture 31: Rabies Virus, Phosphoprotein, Glycoprotein
Document Summary
Is there any cure for rabies virus: rabies virus, vsv (-)ssrna. N is nucleocapsid, g is a spike glycoprotein, l is a polymerase, p is a phosphoprotein associated with the polymerase and m is the matrix. Poly a tails added once mrna is transcribed from (-) strand amount of gene expression depends on how close the gene is to the 3" end (n>p>m>g>l) controlled by the concentration of n protein. Through insects such as mosquitos and sand flies and through mouth to mouth contact between infected animals. Similar to flu + vesicles on the tongue. Saliva(biting) and scratching from infected animals (all mammals can get infected)