(tautomerization) The most common form of guanine is the ketoform, not the enol form.
True
False
What term describes the allowed degree of base pair matchingduring annealing, varying from lots of base-pair mismatches allowedto allowing only perfect base-pair matching.
stringency
aneuploidy
polyploidy
quantitative PCR
restriction fragment length polymorphism
I have an individual with a disease we will call SSI-itis,brought on by extreme exposure to cannabis. I do a southern andfind the gene affected. Another of his classmates exhibits theexact same symptoms, but that gene in hiw is wt. A southern in thesecond student finds a mutation in another gene. This is an exampleof
pleitropy
allelic heterogeneity
locus heterogeneity
dominant traits
recessive traits
penetrance
If a person carrying a dominant allele does not demonstrate thephenotype strongly, but still differs from wt, thisdemonstrates?
haploinsufficiency
penetrance
expressivity
monogenic traits
polygenic traits
I find three alleles for a gene in a fruit fly. One allelecreates the ability for the fly to eat graphite. Another allelecreates the ability for the fly to eat coal. The third alleleallows the fly to eat diamond. These alleles are all dominant, andwt cannot eat any of these substances. Which statement below is themost true?
Upon mating a bunch of the flies carrying these alleles, Ishould not find a fly that can eat graphite, coal, and diamond.
I would consider the ability to eat these substances an exampleof pleitropy because they are all carbon.
I would expect the ability to eat diamond to be dominant to theability to eat graphite.
These flies are demonstrating locusheterogeneity.
Expression vectors in prokaryotes do not make functionaleukaryotic gene products in bacteria very well because
the codon sequence for prokaryotes is different than the codonsequence in eukaryotes
there are no disulfide bridges formed in proteins normally madein prokaryotes
prokaryotic expression vectors cannot translate eukaryticsequences
eukaryotic genes have introns, and prokaryotes don't
eukaryotic genes have exons and prokaryotes don't
Which of the following is not used in PCR amplification ofDNA?
Double-stranded DNA template
Oligonucleotide primers
DNA polymerase
DNA ligase
ddNTPs
I create a knockout mouse using the agouti/black fur systemdiscussed in the online lecture and in the book. When I cross theagouti offspring of the originally engineered mouse, I find a ratioof 2 agouti mice to 1 black furred mouse. What is the bestexplanation?
The gene knocked out was recessive.
The gene knocked out was dominant.
The gene knocked out was a lethal gene.
The knockput was integrated into a random spot, and did notknockput the original gene.
A loss of function mutation is usually recessive, but canactually be a dominant mutation because of what effect?
haploinsufficiency
dominant negative mutations
allelic heterogeneity
locus heterogeneity
pleitropy
A genetic carrier of a disease can have a form of the diseasethat only shows intermittent symptoms, while the full homozygousrecessiuve individual would show all of the symptoms of thedisease.
True
False
Wild type, or wt, refers to the genotype that is the typicalgenotype found in nature. Now read that again. Once more. Nowanswer.
Answer
True
False
