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HMB321H1 Lecture Notes - Lecture 18: Adult Stem Cell, Planarian, Symmetry In Biology

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pucemosquito864
8 Oct 2011
School
UTSG
Department
Human Biology
Course
HMB321H1
Professor
Maria Papaconstantinou

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Document Summary

Hmb321 l18: bret pearson, planarians a new model to disease and regeneration. Prebilateria (not bilaterally symmetric, e. g. sponge and jelly sh) As well as lophotrochozoa (diverse species, e. g. annelids, snails, molluscs) Large uncondensed nucleus is a key characteristic (how it was found) Non-stem cells are differentiated and have condensed, small nuclei. C. elegans have 0 divisions and live only 4 days, whereas mice have more divisions and live up to 3 years, whereas humans have more divisions than mice and live 80 years or so, but . Stem cell is only as good as the lineage that it outputs. Maintenance of correct lineage is unknown process, especially in vertebrates. This maintenance goes awry in our 20s-30s => organismal senescence vs. cancer (in developed countries, in about 1 in 3 humans; hyper-proliferative) Hierarchal => start with non-stem cell (somatic cell) provides info for adult stem cell (asc) Stem cells are de ned by unique biology of self-renewal (multipotency)

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Related Questions

molecular evidence has led taxonomists to group bilaterally symmetrical animals in one of three classes, Deuterostomia, Lophotrochzoa, or Ecdysozoa. Give one distinguishing characteristic of each of these groups other than molecular differences.

About how long does regeneration of a planarian transected horizontally require to form two complete planarians?

For what purposes is planarian regeneration studied?

How does planarian regeneration differ from that of amphibians?

TRUE OR FALSE: Planarian stem cells are different because they are always present, meaning they do not have to undergo clonal expansion before becoming active.

To what phylum do planarians belong?

Which of these areas if amputated from the remaining planarian body will not regenerate to form a new animal?

What is the population of stem cells in planarians responsible for their regenerative properties?

Tissue regeneration is an emerging and exciting biomedical field. As a scientist, choose either an adult stem cell population or embryonic stem cells as a model system to develop a technique for growing artificial limbs in culture. Be sure to explain why you chose your particular stem cell and the drawbacks associated with the one that you did not choose for your experiments.