HMB265H1 Lecture : Notes taken in class
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HMB265H1 Full Course Notes
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20-25% based on first semester material; rest based on second semester material. register on rosi; email sent to you to provide more info on filling out priority ranking forms: to match you to courses you really want. results from mutations in different types of genes: ie. in proto-oncogenes. cells grow out of control, destroying healthy tissue. Failure in mechanisms controlling cell growth, proliferation, and death: result from dna damage from mutations, or types of altered gene expression. normal cell makes decision whether or not to divide based on signals received from neightbouring cells: positive or stimulatory signals to divide, negative signals so stop dividing. cancer cells either insensitive to negative signals or produce own stimulatory signals: autocrine stimulation. normal cells when proliferate, when come in contact with normal cells, stop dividing: one cell layer only if plate normal cells. contact inhibition: tumour cells different don"t receive or listen to signals from neighbouring cells.