IMM250H1 Lecture Notes - Autoimmune Disease, Teratoma, Autoantibody
Document Summary
Final all lecture notes; questions weighted 20 marks worth of questions for lectures after midterm, 10 marks for lectures before midterm; only responsible for papers after the midterm. More psychotic symptoms, seizures more and more bizarre behaviour. Physical symptoms passing out while in hospital put in epilepsy ward, where videos taken. Josep dalmau speciality in autoimmune condition that beings as tumour instead of immune system reacting against self-antigen, reacts first against tumour and then has immune response cross-reacting against other proteins in the body. In all patients seen, female with ovarian tumour well-differentiated tissue . Case series vs case report if clinician seen something interesting, one then case report; if have number of patients with same symptoms, case series. Immunobiology of disorder - not a lot known about this disorder. Treated as autoimmune disease nature of target antigen teratoma expressing self-antigens. Type 2 cateogry where antibodies are responsible for pathology.