LMP299Y1 Lecture Notes - Obstructive Lung Disease, Coronary Artery Disease, Lower Respiratory Tract Infection
12 Apr 2013
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Lecture one: introduction to the biochemistry of human disease. Diagnosis usually requires objective evidence of the pathologic process. Examples are: demonstration of specific biochemical abnormality, visualization of a tumor by ultrasound imaging, finding an inflamed appendix at surgery, isolation of a bacillus or virus, location of a lesion in the tissue by biopsy. Medical laboratory services: pathology (anatomic) includes: histology (tissues) and cytology (cells, hematology includes: blood transfusion medicine and immunology, microbiology includes: bacteriology, virology, parasitology, mycology, biochemistry or clinical chemistry includes: chemicals and chemical markers, genetics includes: molecular diagnostics. Objections of lab medicine: help define as objectively as possible the health and disease, help predict the course of a disease, monitor the effectiveness of treatment, seek for underlying causes of disease, to screen for unsuspected disease. There is a simple measurement of blood glucose: prognosis: ex. Cholesterol level can be used to indicate the percentage of risk: monitoring: ex.
