LMP402 - Lecture 9.doc

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Department
Laboratory Medicine and Pathobiology
Course
LMP299Y1
Professor
All Professors
Semester
Fall

Description
LMP402Fall 2013Lecture 9Leukocyte Emigration Leukocyte emigration in postcapillary venules consists of a series of adhesive interactions between leukocytes and endothelial cells Sequential binding and detachment of adhesion molecules expressed on leukocytes and endothelial cells 1 Tetheringrolling transient adhesive interactions2 Arrest3 Firmstable adhesion leukocyte flattens4 Intravascular crawling 5 Transendothelial migrationdiapedesis which can be betwen or through endothelial cellsIntravital microscopy exteriorizes a pie
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