NFS284H1 Lecture Notes - Lecture 5: Confidence Interval, Blood Lipids, Cardiovascular Disease

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Observational studies: determines an association or correlation between diet and health, types, prospective cohort study, case-control study, cross-sectional study. Statistical adjustment for confounding factors- ex. age adjustment: can only correct for confounders that are identified and measured, uncorrected or unknown confounding --> residual confounding, ex. sleep patterns, physical activity, cannot measure cause and effect. Randomized controlled trials (rct: determines causation between diet and health. Nutrition intervention: metabolic diet, best way to control what people eat, maximize effect of intervention, nutrition education, cheaper, more realistic, see decline in effect. Stroke: cardiovascular events, fatal and non-fatal, ex, myocardial infarction, angina pectoris, pulmonary embolism, transcient ischemic attack, peripheral arterial disease, risk factors, risk factor for cardiovascular disease, ex, hypertension, blood, blood lipids. Ldl cholesterol: hdl cholesterol, ratio: total cholesterol:hd cholesterol, apo b, apo a-i. Nutrition research: relies on results from both intervention trials and observational studies to make dietary recommendations (usually have similar outcomes)

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