NFS284H1 Lecture Notes - Lecture 13: Pyruvic Acid, Prostate Cancer, Bioavailability

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Bmi: underweight = < 18. 5, normal = 18. 5 - 24. 9, overweight = 25 - 29. 9, obese = > 30. 60% of canadians either overweight or obese. Obesity increases the changes in inflammation in the body, which influences other parts of the body such as resistance in other organs. Carrying more body fat means you release more pfa (pre fatty acids) Too many pfa pouring into muscle/liver produces a series of byproducts that are toxic to you called lipotoxicity (which can shutdown insulin sensitivity in the cell) Vast majority of individuals with diabetes carry more body weight than is healthy. Obesity tends to reduce the risk of breast cancer in premenopausal women. Prostate cancer is treated better in leaner men, but the potential for risk in prostate cancer is varied. Apoptosis: method the body uses to get rid of damaged cells it cannot repair.

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