PSL201Y1 Lecture Notes - Lecture 6: Axon Hillock, Excitatory Synapse, Inhibitory Postsynaptic Potential
Document Summary
Resulting graded potential which is either excitatory or inhibitory (epsp or ipsp) and result of all this combined summed up effect is called neural integration. Axon hillock is also known as the trigger zone tip of the axon first patch of membrane that contains lots of na+ and k+ channels and is able to fire an action potential. Divergence arrangement of neuron single presynaptic neuron connects with many postsynaptic neurons. Many presynaptic terminals converging on a single postsynaptic neuron convergence. The summing of input from various synapses (convergent or divergent) at the axon hillock of the postsynaptic neuron to determine whether the neuron will generate action potentials. Graded potentials can sum process of temporal and spatial summation. Depolarize membrane to -55 mv to fire to generate an action potential individually neurons a and b , even though excitatory, cant generate an epsp strong enough in magnitude to reach.
