PSL300H1 Lecture Notes - Lecture 24: Pituitary Gland, Hypotension, Diuretic
Document Summary
Anti-diuretic hormone (adh) (vasopressin) v primary function: increases water reabsorption in the kidneys. Psl300 human physiology i v adh needs to travel through the endothelial cells of the blood vessels: there are pores between the endothelial cells that the. Adh can pass through to get to their target cells in the kidneys v the target cells called principal cells: they have the adh receptor on their plasma surface, g protein signalling. Adh binds to the receptor on the plasma membrane. Regulation of adh release v changes in osmolarity: detected by osmoreceptors in hypothalamus, most potent stimulus v blood pressure changes, baroreceptors detect reduced stretch in. Aortic and carotid arteries v alcohol inhibits adh v adh needs to be released when water needs to be absorbed: controlled by negative feedback v low blood pressure is detected by baroreceptors, sense the reduced stretch of. Walls of the atria of the heart.
