PSL301H1 Lecture Notes - Lecture 17: Mechanical Ventilation, Freediving, Hypoventilation
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PSL301H1 Full Course Notes
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What is the treatment for congenital central hypoventilation syndrome: o2 goes down, co2 goes up eventually triggers breathing. Starts at a lower point -> takes longer time to go up and reach a point where breathing is triggered. Direct relationship: respiratory rate (breaths/minute, tidal volume (ml) Oxygen levels (low oxygen -> increased sensitivity to co2) Located in the medulla and monitor h+ in csf and arterial circulation. Carotid and aortic bodies which monitor arterial co2/h+ Gpr4 in the rtn that detects protons in the csf. Ventilation doesn"t go up as much in response to an increase in co2 (up to 8%) Yes to detect h+ and regulate ventilation. Cessation of airflow without respiratory effort disorder in the raphe neurons. Idiopathic: cheyne stokes breathing can be caused by heart failure, narcotic, ondine"s curse (congenital central hypoventilation syndrome) Mechanical ventilation during sleep ppv in early life and bipap later in life.
