PSL301H1 Lecture Notes - Lecture 3: Naloxone, Red Blood Cell, Partial Pressure

• School: UTSG
• Department: Physiology
• Course: PSL301H1
• Professor: Christine Wong

Document Summary

Lecture 3 respiratory gas exchange and transport. Proportions of co2 in blood v co2 is mostly transported in the form of bicarbonate in plasma and red blood cells v image: graph showing the proportion of carbon dioxide in. Most of it is bicarbonate that transports oxygen. Clinical focus: respiratory acidosis v case study: unconscious and probable overdose of narcotics, ph = 7. 27 (normal ph is 7. 4, paco2 = 58 mmhg (normal pco2 is 40 mmhg, [hco3. ] = 26 meq/l (normal value = 24 meq/l) v causes: paco2 is above normal but [hco3. Hypoventilation is the cause of acidosis: narcotic-induced respiratory depression. Partial pressure of carbon dioxide increases v causes include above normal: when the partial pressure of carbon dioxide is high, but the concentration of bicarbonate is normal. No gas exchange to get rid of the carbon dioxide and is producing more hydrogen ions when the carbon dioxide reacts with water: hypoventilation.