PSY492H1 Lecture Notes - Lecture 2: Ligand-Gated Ion Channel, Adenylyl Cyclase, Chemical Synapse
Document Summary
Lecture 2: modifiable synapses and molecules for simple memory. Neurons is composed of a cell body, dendrites, an axon, and axon terminals. Flow of information is from cell body towards axon then axon terminals. Different neurons exhibit different features (e. g. purkinje cell of cerebellar cortex is known for wide and extensive branching) Synapse: connection between two neurons (most synapses in cortex have mushroom/bulb shape synapse) Nt: if nt is excitatory it will allow influx on ions (e. g. na+) into postsynaptic membrane and this changes the excitability of membrane (i. e. action potential) Neurotransmitters (nt) are small molecules that transmit information from presynaptic neurons to the postsynaptic neuron (e. g. glu, gaba, da, ne, ach, and 5ht) There are two types of receptors in postsynaptic memebrane: ionotropic: directly allow ion passage ligand-gated ion channels: open or close in response to nt (e. g. glu receptors such as. Releasing phosphate = decreasing energy (e. g. atp has more energy than.
