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Lecture 6

Lecture 6 - Sensory Processing II

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University of Toronto St. George
Franca Placenza

Taste Stimuli 1. The basic taste stimuli o Saltiness o Sourness o Sweetness o Bitterness o Umami = the taste of meat (savory) 2. Tongue o Primary taste organ o Covered with papillae o 3 types of papillae Circumvallate papillae - largest, found at back of tongue, are 9 50% of cell receptor cells occur by these Foliate papillae - second largest, found on sides of tongue Fungiform papillae - smallest, found near tip of tongue Contain 6 taste buds each o Each papillae : Contains several hundred taste buds Taste buds are clusters of taste receptor cells 3. Taste receptor cells o Saliva has access to these (in the crevasses of the papillae) o Project toward the surface of the tongue Apical end has thing extensions (microvilli - an opening that saliva enters in) that are clustered in taste pores Basal end innervated by gustatory nerve fibers o Basal cells - progenitor cells which become new taste cells every 2 weeks Are the baby cells that make the new taste receptor cells Not all sensory systems have regenerating cells Chemotransduction in Taste Cells 4. Saltiness o Salt-sensitive taste cells have special Na+ channel (different than ones discussed before) EX = amiloride-sensitive sodium channel Always open channels that recognize sodium o Na+ in salty foods enter cell through amiloride-sensitive sodium channel resulting in depolarization Current passively spreads down o Voltage-gated Na+ and Ca2+ channels open in response to depolarization, triggering neurotransmitter release These channels found near the bottom of the cell (different from ones above) Ca2+ allows vesicles to produce (similar as in neurotransmitters) 5. Sourness
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