BIOL 312 Lecture Notes - Lecture 40: Lyme Disease, Wolbachia, Onchocerciasis

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Mechanical transfer: no replication of pathogen in vector. Biological transfer: pathogen replication in vector, specific association, transfer requires vector, parasite, host. Multiple: more than 1 vertebrate host, including 1o reservoir spp. in which parasite can persist long term. Determine outcomes of vectored diseases: ecology of vector (distribution, abundance, preference for biting humans). Suitability of vector for pathogen development and transmission. Lyme disease: caused by spirochete, transmitted by ticks. Plague: caused by yersinia pestis, transmitted by fleas. Arboviruses = arthropod borne viruses: replicate inside vector and vertebrate host. Encephalitis: caused by several viral diseases using mosquitoes as the host. Malaria: asexual phase in humans, sexual phase in mosquitoes. Caused by 4 species of plasmodium in over 30 species of mosquito. Malaria reduces mosquito fecundity but resistance is also costly. Wilson & michener"s definition: 1) division of labour: caste system, involving sterile or nonreproductive individuals assisting those that reproduce.

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