BIOL 3530 Lecture Notes - Lecture 3: Telomerase, Organelle, Exocytosis

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plumcamel14

29 Aug 2020

School

University of Windsor

Department

Biological Sciences

Course

BIOL 3530

Professor

Andrew Hubberstey

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Document Summary

The importance of ran in getting proteins in and out the nucleus. It use a single on and off switch to control this process and it is the main trigger that allows import and export. There is different types of nuclear proteins that have to enter the nucleus at a specific time and they are regulated. It is a dynamic process so in and out. Nuclear envelope which is a membrane structure that have to be broken down every time in mitosis. The chromatin itself is a trigger which bring the er tubules into place where dna is and the dna is the attraction so the tubules start to fuse and form with the lamen a new nuclear envelope. You need tickets to get in and out the nucleus. Trans-membrane transport system: where protein synthesized in cytoplasm make their way into mitochondria. There are some proteins that exist in the inter membrane space.

Related Questions

One effective learning strategy when trying to learn largeamounts of factual information is to group items, or âchunkâ. Youshould include all important structures of the cell (this includescell membrane and membrane adaptations as well as organelles).Examples of general categories could be location, function,morphology, etc. Your categorization groups must tell the viewersomething about the structures. Once your structures are groupedaccording to the characteristics they share, you should include ashort phrase about what differentiates them from each other withinthe group. Citation of your source material must be present.

List of Organelles:

Nucleus, Nuclear envelope/membrane, Nucleolus, Ribosomes,Endoplasmic reticulum, Golgi apparatus, Mitochondria, Plasmamembrane, Cytoskeleton, Transport/secretory vesicles,Phagosomes/endosomes-including sorting & recycling endosomes,Lysosomes, Peroxisomes, Lipid droplets, Glycogen granules

I started this assignment and was going to go withfunction and morphology. Below is what I have so far, but I'mhaving a difficult time coming up with a short phrase for each anddistinguishing between the organelles that can change shape/morphand those that cannot. I am open to changing the categories that Ihave chosen to chunk. I've never used this technique before so it'sa new concept for me.

Function

Protein Synthesis â Nucleus, Nuclear envelope, Nuclear porecomplex, Ribosomes, Rough endoplasmic reticulum, Golgi apparatus,Plasma membrane

Energy Production â Mitochondria, Lipid droplets, Glycogengranules

Transportation â Transport vesicles, Phagosomes,Cytoskeleton

Metabolism â Lysosomes aid in digestion, Peroxisomes oxidizefatty acids

Morphology

Ability to change shape â Mitochondria, Cell membrane, Nuclearenvelope,

Inability to change shape â Nucleus, Nuclear envelope,

erinporpoise390

1. The histones that form the core of the nucleosome get into the nucleus by which of the following?

a) Passive diffusion through nuclear pores

b) Selective and facilitated active transport through nuclear pores

c) Ribosomes located in the nucleus synthetize histones in the nucleus

d) Histones are made at the ER membrane and then diffuse to the nucleus

2. Membrane proteins that belong to the golgi, lysosome, or plasma membrane first pass through which organelle before reaching their final subcellular destination?

a) The golgi apparatus

b) The smooth ER

c) The nucleus

d) The ER membrane

e) The ER lumen

3. Where in the cell would a ribosomal protein be located if it has had its nuclear export signal inactivated (non-functional or non-existent).

a) The protein would be found in the ER lumen

b) The protein would remain in the nucleus

c) The protein would be secreted

d) The protein would remain in the cytoplasm

e) The protein would be in the ER membrane

4. Where would be the final destination of a protein if it contained a NLS anywhere in the protein sequence (and which is exposed to the cytoplasm after protein folding) but also contained an ER signal sequence at the carboxy terminus?

a) The ER lumen

b) The nucleus

c) The cytoplasm

d) The inner nuclear membrane

e) The ER membrane

5. The sequence K-D-E-L serves as a retention/retrieval signal for ER proteins.

a) True

b) False

6. The following are true for both cell membrane proteins and secretory proteins EXCEPT?

a) Precursors of the mature proteins contain signal sequence.

b) Both types of proteins contain stop-transfer sequences

c) Both types of proteins enter the ER while being synthetized

d) Both types of proteins pas through the golgi apparatus

e) Both are carried by clatherin-coated vesicles

7. If you isolate a regulated secreted protein from a secretory/storage vesicle and inject it into the cytosol, is will?

a) Be secreted through channels in the plasma membrane

b) Be taken up into secretory vesicle and secreted

c) Remain in the cytosol until it is degraded

d) Be taken up into the rough ER and follow the secretory pathway

goldmanatee250

1)A friend works in a biotechnology company and has discovered a drug that blocks the ability of ran the echange GDP for GTP. What is the most likely effect of this drug on nuclear transport?

a)nuclear transport receptors would be unable to bind cargo.

b)nuclear transport receptors would be unable to enter the nucleus

c)nuclear transport receptors would be unable to release their cargo in the nucleus

d)nuclear transport receptors would interact irreversibly with the nuclear pore fibrils

2)After isolating the rough endoplasmic reticulum the the rest of the cytoplasm, you purify the mRNAs attached to it. Which of the following proteins do you expect the mRNA from the rough endoplasmic reticulum to encode?

a) plasma membrane proteins

b)ER membrane proteins

c)Soluble secreted proteins

d)all of the above

3)For both actin and microtubule polymerization, nucleotide hydrolysis is important for?

a)stablilizing the filaments once they are formed

b)increasing the rate at which subunits are added to the filaments

c)promoting nucleation of filaments

d)decreasing the binding strenth between subunits on filaments

indigohare858

BIOL 3530 Lecture Notes - Lecture 3: Telomerase, Organelle, Exocytosis

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