BIOC 3100 Lecture 5: 5 - Citric Acid Cycle

• School: University of Windsor
• Department: Chemistry and Biochemistry
• Course: BIOC 3100
• Professor: siyarampandey

Document Summary

Take pyruvate through the cac or ta or kc (same thing) An oxidative reaction converted to acetyl coenzyme. Reactions (8 of them) and tca cycle or cac. All these reactions take place in the mitochondria. They generate nadh and it utilized by the mitochondria only! Cannot be recycled back by any other method. 3 of them produce nadh, 1 of them produces 1 fadh. Reducing currencies which are eventually taken up on the mitochondria membranes, where they are oxidized. Eventually transferred to oxygen which is converted to. Without using o2 all converted to co2 in the citric acid cycle Using o2 you can cash the cheques. They measured the oxygen concentration in the yeast broth. Hypothesized that after glycolysis, something converted the pyruvate to co2 consumption was gone. Malonate was put in the reaction mixture the o2. Malonate sat in the active site succinate could not be converted to the product.