Anatomy and Cell Biology 3309 Lecture Notes - Lecture 22: Splenic Artery, Red Pulp, White Pulp
19 Aug 2019
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Document Summary
Functions: humoral responses production of antibodies against circulating antigens, disposal of defective red blood cells hemoglobin recycled. Storage of platelets in some species: gross anatomy. Smooth convex surface: hilum at the concave surface entrance/exit for arteries, veins, & efferent lymphatics. Easy to injure spleen and very difficult to repair. Is a secondary lymphoid organ: area where programmed mature t cells & b cells will go to monitor blood for infection & respond to immune challenges. T and b cells undergo clonal expansion here. Plasma cells will be produced by b cells in the spleen, and they will release antibodies. Supporting structures: dict capsule, trabeculae extensions of the capsule into the parenchyma. Contain trabecular arteries and veins (whereas the lymph nodes don"t!: reticular fibres. Parenchyma held together by reticular fibres: white pulp mostly lymphocytes. Is a splenic nodule: red pulp mostly blood eosinophilic.
