Anatomy and Cell Biology 3309 Lecture Notes - Lecture 8: Splenic Vein, Myofibroblast, Antigen Presentation

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Red pulp is still very cellular but we have more open spaces. Red pulp is some-what similar to the medula in the lymph node in that we have sinuses (more open spaces) and splenic cords which are similar to medulary cords. Red pulp is supported by reticular fiber, again not floating aruound. Splenic sinusoids play a very important role in the function of red pulp (filtering the blood). They are basically capillaries that are very leaky. Splenic cords like medullary cords have reticular cells and fibers in there, you also have macrophages, dendritic cells and lymphocytes, plasma cells (differentiated b cells) as well as granulocytes, Again, the central artery comes off trabecular artery and continues all the way down where you have a penicillar arteriole coming off it in the red pulp region. Those penicillar arterioles have 2 kinds of structures. They can either empty in the parenchyma (blind; they are open, but this isn"t seen much).

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