Biochemistry 2280A Lecture Notes - Lecture 14: Arginine, Chromosome, Chromatin

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Bonnie Mac Lachlan

Document Summary

Unit 3: nucleic acids lesson 14: nucleic acid structure (oct. 31st 2017) Ribonucleoside: carbohydrate, always in beta conformation, 5-carbon sugar, can attach a nitrogenous base, sugar and a base, cytidine, n-glycosidic bond. Ribonucleotide: added phosphate group, base, sugar and phosphate, tide has added phosphate, cytidine monophosphate, also a nucleoside monophosphate, triphosphate has three phosphate groups, cytidine triphosphate, also a nucleoside triphosphate. Lost oh, o(cid:374)l(cid:455) ha(cid:448)e a h(cid:455)droge(cid:374) o(cid:374) the (cid:1006)" (cid:272)ar(cid:271)o(cid:374): called deoxycytidine triphosphate, also a deoxynuleoside triphosphate. Polynucleotides: phosphodiester linkage, sequence gatc, can go on for any length, no set limit, chemical differences at each end, oh group is (cid:1007)" e(cid:374)d, 5" e(cid:374)d is o(cid:374) opposite side (cid:894)(cid:272)ar(cid:271)o(cid:374) is (cid:374)ot atta(cid:272)hed to a(cid:374)other sugar(cid:895). Nucleosome core particles: 8 total proteins (2 copies of each 4), shaped like a hockey puck, dna is wrapped around the histone, 1. 7 turns, h3 histone tail.