Biochemistry 2280A Lecture Notes - Lecture 7: Activation Energy, Isomerization, Covalent Bond
12 Dec 2016
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Document Summary
Lack of vitamin c (ascorbic acid) in diet. Caused by a defect in the synthesis of collagen: fancy word for antibodies = immunoglobulins. Immune response is triggered by foreign macromolecules (antigens) Soluble proteins that recognize and tag antigens to kill them. Multiple types of immunoglobulins (a, d, e, g, m) igg is the main form found in blood: igg. Billions of iggs are made by an individual. Different iggs have similar sequences, other than in certain regions. Short hyper-variable regions within these (regions that most vary to accommodate different antigens) Variable regions similar but not identical to constant regions. Immunoglobulins are made of a light chain and a heavy chain (light chain is smaller) Each of them have a variable region that changes to accommodate the type of antigen they"re coming into contact with. Is a tetramer: 4 polypeptide chains with two identical pairs.
