Biochemistry 2280A Lecture Notes - Lecture 1: Microrna, Post-Translational Modification, Epigenetics
12 Dec 2016
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Cellular level of what makes your body works. How the cells work together to get the tissues to work: molecules of life . Proteins, lipids, carbohydrates, nucleic acids: central dogma of molecular biology. It is authoritative and not to be disputed, doubted or diverged from. In science, we tend to refer something as a dogma for which we have a factual base. Central dogma we"re going to be talking about is how nucleic acids code for proteins. Dna acts as template to produce rna rna translated into protein (made of amino acids) The core central dogma used to be that there are these two steps that must occur to get from your genome to protein. But/ now we know there are other steps! Microrna: can bind to pieces of genome and block transcription. Post-translational modification: proteins can be altered as well. E. g. phosphorylation, acetylation etc: genotype: sum of inheritable potential (basically your genome)
